WomenCo.

My best friend worked for another friend of mine and on Friday, my best friend quit.  We talked about it and she says she doesn't want to work there any more.  I have been unemployed since the end of June and want to know if it would be wrong for me to ask the owner, also a friend of mine for the position.  It is not like my best friend got fired from a job she loves.  She did get upset, though and quit.  When I talked to my best friend yesterday, she said she knew she needed to talk to the employer because she still cares about her, but then today she when I asked my best friend if she talked to her, she told me she wasn't going to that the employer knows she quit and she was just kind of cold about it.  I had thought that maybe they would work things out but now I think it is too late.  So am I wrong in pursuing this position?  Please give me your opinions.  Thanks!

Not unethical.  Consider, however, whether it might cause friction between you and your best friend who quit the position, and whether you're okay with the possibility of friction.  Also evaluate your friendship with the boss and whether you're okay with possibly losing that friendship if the job doesn't work out.